Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712740 | 0.93 | KMT2A (0.54) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL6622934 | 0.93 | MAPT (0.53) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL6981476 | 0.92 | MAPT (0.50) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL7410741 | 0.89 | AKR1B1 (0.47) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL6985338 | 0.87 | AKR1B1 (0.66) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL21187892 | 0.85 | MAPT (0.68) | KMT2ATDP1SLC6A2SLC6A3MAPT | |
| SCHEMBL22479070 | 0.85 | AKR1B1 (0.53) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL22479063 | 0.85 | PIM1 (0.60) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL4924372 | 0.85 | AKR1B1 (0.53) | KMT2ATDP1SLC6A2SLC6A3MAPT | |
| SCHEMBL15714290 | 0.84 | PIM1 (0.63) | KMT2ATDP1SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739350-A | COMPOUNDS CAPABLE OF BEING LINKED TO MONOCLONAL ANTIBODIES FOR DELIVERY TO TARGET CELLS | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-14 | — | — | US | disclosed |