SCHEMBL2346356

SCHEMBL2346356

Nc1nc2nc(CCOCCO)[nH]c2c(=O)[nH]1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PNP P00491 9/20 0.51
HSD17B10 Q99714 2/20 0.42
USP2 O75604 1/20 0.42
TSHR P16473 1/20 0.42
EDNRA P25101 1/20 0.42
HTR2A P28223 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
HBB P68871 1/20 0.42
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
FGFR1 P11362 1/20 0.40
FGFR2 P21802 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37957 0.87 PNP (0.53) PNPHSD17B10USP2TSHREDNRA
SCHEMBL350396 0.85 PNP (0.61) PNPHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL15545139 0.84 PNP (0.48) PNP
SCHEMBL216786 0.83 PNP (0.47) PNP
SCHEMBL5935062 0.82 PNP (0.70) PNPHSD17B10HBBKDM4EMEN1
SCHEMBL14079841 0.79 PNP (0.66) PNPHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL9806967 0.77 PNP (0.63) PNPHSD17B10HBBKDM4EMEN1
SCHEMBL667795 0.76 PNP (0.61) PNPHSD17B10KDM4EMEN1ALDH1A1
SCHEMBL441796 0.76 PNP (0.61) PNPHSD17B10HBBKDM4EMEN1
SCHEMBL7617798 0.76 PNP (0.53) PNPHSD17B10KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444969-B1 Absorbent article KAO CORP (JP) 2011-08-31 EP disclosed
US-20040158216-A1 Absorbent article KAO CORPORATION (JP) 2004-08-12 US disclosed
EP-1444969-A1 Absorbent article Kao Corporation (JP) 2004-08-11 EP disclosed