Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 10/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25271966 | 0.88 | KCNJ1 (0.46) | KCNJ1KCNH2KDM4ENPC1NR2F2 | |
| SCHEMBL6852082 | 0.88 | KCNJ1 (0.46) | KCNJ1KCNH2KDM4ENPC1NR2F2 | |
| SCHEMBL3420319 | 0.88 | KCNJ1 (0.46) | KCNJ1KCNH2KDM4ENPC1NR2F2 | |
| SCHEMBL31539506 | 0.88 | KCNJ1 (0.46) | KCNJ1KCNH2KDM4ENPC1NR2F2 | |
| Hydrochloric Acid SCHEMBL30287913 | 0.87 | KCNJ1 (0.45) | KCNJ1KCNH2KDM4ENPC1NR2F2 | |
| SCHEMBL19460959 | 0.83 | SIGMAR1 (0.40) | SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL8603208 | 0.83 | SIGMAR1 (0.40) | SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL4092491 | 0.83 | KCNJ1 (0.49) | KCNJ1KCNH2SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL15709381 | 0.82 | KDM4E (0.47) | KCNJ1KCNH2SIGMAR1KDM4ESMN1; SMN2 | |
| SCHEMBL9483806 | 0.81 | KCNH2 (0.40) | KCNJ1KCNH2KDM4ENPC1NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756065-A | DIAGNOSTIC CHELATES FOR ANTIBODIES AND RADIOACTIVE MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1998-05-26 | — | — | US | claimed |
| US-5756065-A | DIAGNOSTIC CHELATES FOR ANTIBODIES AND RADIOACTIVE MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1998-05-26 | — | — | US | disclosed |