Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19460959 | 1.00 | SIGMAR1 (0.40) | SIGMAR1S1PR1ALDH1A1FOLH1LMNA | |
| SCHEMBL8718217 | 0.93 | SIGMAR1 (0.36) | SIGMAR1S1PR1ALDH1A1FOLH1LMNA | |
| SCHEMBL15904929 | 0.87 | FOLH1 (0.45) | SIGMAR1S1PR1FOLH1 | |
| SCHEMBL5864632 | 0.87 | FOLH1 (0.45) | SIGMAR1S1PR1FOLH1 | |
| SCHEMBL17119211 | 0.87 | FOLH1 (0.45) | SIGMAR1S1PR1FOLH1 | |
| SCHEMBL1079200 | 0.87 | FOLH1 (0.45) | SIGMAR1S1PR1FOLH1 | |
| SCHEMBL1996255 | 0.87 | FOLH1 (0.45) | SIGMAR1S1PR1FOLH1 | |
| Hydrochloric Acid SCHEMBL31226505 | 0.86 | FOLH1 (0.44) | SIGMAR1S1PR1FOLH1 | |
| SCHEMBL8717979 | 0.83 | KCNJ1 (0.49) | SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL436094 | 0.82 | LMNA (0.45) | S1PR1FOLH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756065-A | DIAGNOSTIC CHELATES FOR ANTIBODIES AND RADIOACTIVE MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1998-05-26 | — | — | US | claimed |
| US-5756065-A | DIAGNOSTIC CHELATES FOR ANTIBODIES AND RADIOACTIVE MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| US-5739323-A | Carboxamide modified polyamine chelators and radioactive complexes thereof for conjugation to antibodies | THE DOW CHEMICAL COMPANY (US) | 1998-04-14 | — | — | US | disclosed |