Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718106 | 1.00 | ABCB1 (0.47) | ABCB1ABCG2RENALOX15ALOX12 | |
| SCHEMBL8718945 | 0.91 | ALOX15 (0.53) | ALOX15ALOX12KMT2ASIGMAR1CYP2D6 | |
| SCHEMBL8718948 | 0.91 | ALOX15 (0.53) | ALOX15ALOX12KMT2ASIGMAR1CYP2D6 | |
| Hydrochloric Acid SCHEMBL11849010 | 0.87 | REN (0.46) | ABCB1ABCG2RENALOX15ALOX12 | |
| SCHEMBL8713614 | 0.85 | ABCB1 (0.43) | ABCB1ABCG2BCHEKDM4ELMNA | |
| SCHEMBL8713617 | 0.85 | ABCB1 (0.43) | ABCB1ABCG2BCHEKDM4ELMNA | |
| SCHEMBL8716669 | 0.84 | ALOX15 (0.51) | ALOX15ALOX12KMT2ASIGMAR1CYP2D6 | |
| SCHEMBL8716667 | 0.84 | ALOX15 (0.51) | ALOX15ALOX12KMT2ASIGMAR1CYP2D6 | |
| SCHEMBL8713349 | 0.83 | ALOX15 (0.56) | ALOX15ALOX12KMT2ASIGMAR1CYP2D6 | |
| SCHEMBL8713353 | 0.83 | ALOX15 (0.56) | ALOX15ALOX12KMT2ASIGMAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |