Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 17/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718271 | 1.00 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8717494 | 0.90 | CBX7 (0.45) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8717498 | 0.90 | CBX7 (0.45) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8714398 | 0.86 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8714400 | 0.86 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8716580 | 0.86 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8716583 | 0.86 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8713656 | 0.86 | LMNA (0.47) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8713658 | 0.86 | LMNA (0.47) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL8719065 | 0.85 | HDAC8 (0.43) | SLC6A4SLC6A2SLC6A3CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |