Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718566 | 1.00 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3TSHRHPGD | |
| SCHEMBL8713904 | 0.90 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3AOC3ADRB2 | |
| SCHEMBL8713907 | 0.90 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3AOC3ADRB2 | |
| SCHEMBL8714240 | 0.87 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3AOC3ADRB2 | |
| SCHEMBL8714237 | 0.87 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3AOC3ADRB2 | |
| SCHEMBL8716204 | 0.85 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3AOC3ADRB2 | |
| SCHEMBL8716202 | 0.85 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3AOC3ADRB2 | |
| SCHEMBL8716815 | 0.84 | TSHR (0.40) | TSHRGABRA1GABRB2ALDH1A1POLB | |
| SCHEMBL8716819 | 0.84 | TSHR (0.40) | TSHRGABRA1GABRB2ALDH1A1POLB | |
| SCHEMBL8716159 | 0.84 | CFD (0.43) | SLC6A2SLC6A4SLC6A3AOC3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |