Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716815 | 1.00 | TSHR (0.40) | TSHRGABRA1GABRB2TAAR1MAPT | |
| SCHEMBL8714091 | 0.91 | TAAR1 (0.38) | TSHRTAAR1ALDH1A1DPP4DPP7 | |
| SCHEMBL8714092 | 0.91 | TAAR1 (0.38) | TSHRTAAR1ALDH1A1DPP4DPP7 | |
| SCHEMBL8715448 | 0.84 | TAAR1 (0.37) | TAAR1DPP4DPP7 | |
| SCHEMBL8718562 | 0.84 | SLC6A2 (0.42) | TSHRGABRA1GABRB2POLBALDH1A1 | |
| SCHEMBL8715445 | 0.84 | TAAR1 (0.37) | TAAR1DPP4DPP7 | |
| SCHEMBL8718566 | 0.84 | SLC6A2 (0.42) | TSHRGABRA1GABRB2POLBALDH1A1 | |
| SCHEMBL8714177 | 0.83 | KMT2A (0.39) | TAAR1MEN1KMT2AMAPK1 | |
| SCHEMBL8714178 | 0.83 | KMT2A (0.39) | TAAR1MEN1KMT2AMAPK1 | |
| SCHEMBL8716697 | 0.82 | MPO (0.40) | TSHRTAAR1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |