SCHEMBL8718892

SCHEMBL8718892

O=S(=O)(O)CCc1c[c]ncc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
KMT2A Q03164 1/20 0.33
PTGS1 P23219 1/20 0.31
PDE4A P27815 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819155 0.75 KMT2A (0.53) NPC1KMT2A
SCHEMBL4824620 0.75
SCHEMBL17508105 0.73 KMT2A (0.51) NPC1KMT2A
SCHEMBL9479042 0.73 KMT2A (0.51) NPC1KMT2A
SCHEMBL9343856 0.73 KMT2A (0.51) NPC1KMT2A
SCHEMBL1515146 0.70
SCHEMBL8847552 0.69 LMNA (0.36) NPC1KMT2A
Formamide SCHEMBL11293812 0.69 NPC1 (0.47) NPC1KMT2A
SCHEMBL294392 0.68 TDP1 (0.39) NPC1KMT2APTGS1
SCHEMBL14720079 0.68 KMT2A (0.50) NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811081-A Use of hydroxybenzotriazoles for enhancing the sun protection factor of cellulosic fibre materials CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-22 US claimed
EP-0708197-A2 Utilisation of hydroxybenztriazoles for increasing the sun-ray filter index of fibrous cellulosic materials CIBA-GEIGY AG (CH) 1996-04-24 EP claimed
US-5811081-A Use of hydroxybenzotriazoles for enhancing the sun protection factor of cellulosic fibre materials CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-22 US disclosed
EP-0708197-A2 Utilisation of hydroxybenztriazoles for increasing the sun-ray filter index of fibrous cellulosic materials CIBA-GEIGY AG (CH) 1996-04-24 EP disclosed