SCHEMBL8719014

SCHEMBL8719014

N#CCc1cccc2c1C(CC#N)c1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.39
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
IDO1 P14902 1/20 0.35
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
GPR3 P46089 1/20 0.31
FFAR1 O14842 2/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2435025 0.80 HTR2A (0.52) HTR2AIDO1CA1CA2GPR3
SCHEMBL7114057 0.74 HTR2A (0.36) HTR2A
SCHEMBL31274740 0.68 HTR2A (0.42) HTR2AALDH1A1HPGDCA1CA2
SCHEMBL2230423 0.68 HTR2A (0.42) HTR2AALDH1A1HPGDCA1CA2
SCHEMBL8715922 0.68 HTR2A (0.42) HTR2AALDH1A1HPGDCA1CA2
SCHEMBL3485947 0.68 HTR2A (0.42) HTR2AALDH1A1HPGDCA1CA2
SCHEMBL1945874 0.67 ALDH1A1 (0.56) ALDH1A1HPGDFFAR1FFAR4
SCHEMBL29809738 0.67 ALDH1A1 (0.56) ALDH1A1HPGDFFAR1FFAR4
SCHEMBL10998124 0.66 HTR2A (0.48) HTR2AIDO1CA1CA2GPR3
SCHEMBL30399874 0.66 HTR2A (0.48) HTR2AIDO1CA1CA2GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5807974-A POLYARYLENEVINYLENE RESIN KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-09-15 US disclosed