SCHEMBL8715922

SCHEMBL8715922

BrCc1cccc2c1C(CBr)c1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.42
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
TSHR P16473 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
ATM Q13315 1/20 0.32
CYP1A2 P05177 1/20 0.31
MAPK1 P28482 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
NCOR2 Q9Y618 1/20 0.31
GPR3 P46089 2/20 0.31
TDO2 P48775 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8832034 0.78 HTR2A (0.58) HTR2ACA1CA2TSHRKMT2A
SCHEMBL2230423 0.71 HTR2A (0.42) HTR2ACA1CA2TSHRMEN1
SCHEMBL3485947 0.71 HTR2A (0.42) HTR2ACA1CA2MEN1KMT2A
SCHEMBL31274740 0.71 HTR2A (0.42) HTR2ACA1CA2TSHRMEN1
SCHEMBL5792714 0.69 ALDH1A1 (0.45) HTR2ACA1CA2TSHRMEN1
SCHEMBL31275339 0.68 TDO2 (0.47) HTR2ACA1CA2TSHRKMT2A
SCHEMBL8719014 0.68 HTR2A (0.39) HTR2ACA1CA2GPR3ALDH1A1
SCHEMBL6759445 0.68 HTR2A (0.39) HTR2ACA1CA2CYP1A2GPR3
SCHEMBL2306813 0.68 TDO2 (0.47) HTR2ACA1CA2TSHRKMT2A
SCHEMBL2672463 0.67 BCHE (0.41) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5807974-A POLYARYLENEVINYLENE RESIN KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-09-15 US disclosed