SCHEMBL8719147

SCHEMBL8719147

COc1cc(C=O)ccc1OCCCCCCOc1ccc(C=O)cc1OC

nearest known ligand 0.87

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.87
ALDH1A1 P00352 12/20 0.70
TSHR P16473 1/20 0.70
MAPT P10636 10/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
LMNA P02545 4/20 0.68
NPSR1 Q6W5P4 2/20 0.68
HTT P42858 2/20 0.68
CYP2C9 P11712 3/20 0.64
NPC1 O15118 1/20 0.64
RAB9A P51151 1/20 0.64
HPGD P15428 7/20 0.63
CYP1A2 P05177 2/20 0.63
CYP2C19 P33261 2/20 0.63
HSP90AA1 P07900 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.62
CYP2D6 P10635 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9442183 1.00 FDPS (0.87) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL9442186 0.98 FDPS (0.90) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL2818009 0.94 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL30360543 0.94 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL30360546 0.94 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL8310250 0.94 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL10417162 0.94 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL5689116 0.94 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL8907835 0.94 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL30360545 0.94 FDPS (0.77) FDPSALDH1A1TSHRMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3487931-B1 HIGH-STRENGTH RUBBER COMPOSITION MICHELIN & CIE (FR) 2022-04-20 EP disclosed
US-10647848-B2 Rubber composition with a high level of fluidity based on an aromatic aldehyde and an aromatic polyphenol COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-05-12 US disclosed
EP-3390536-B1 RUBBER COMPOSITION WITH A HIGH LEVEL OF FLUIDITY BASED ON AN AROMATIC ALDEHYDE AND AN AROMATIC POLYPHENOL MICHELIN & CIE (FR) 2019-10-16 EP disclosed
WO-2018015668-A1 HIGH-STRENGTH RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-01-25 WO disclosed
WO-2017103404-A1 RUBBER COMPOSITION WITH A HIGH LEVEL OF FLUIDITY BASED ON AN AROMATIC ALDEHYDE AND AN AROMATIC POLYPHENOL COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-06-22 WO disclosed
US-5807974-A POLYARYLENEVINYLENE RESIN KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647848-B2 Rubber composition with a high level of fluidity based on an aromatic aldehyde and an aromatic polyphenol AHR, POP1, RER1 FDPS 2399/4885ALDH1A1 85/4885TSHR 4629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.