Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16329447 | 0.92 | RAB9A (0.33) | ALDH1A1KDM4EPKMALOX15HTT | |
| SCHEMBL5081272 | 0.90 | RAB9A (0.32) | ALDH1A1KDM4EPKMRAB9A | |
| SCHEMBL5081270 | 0.90 | RAB9A (0.32) | ALDH1A1KDM4EPKMRAB9A | |
| SCHEMBL5278699 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KDM4EPKMALOX15HTT | |
| SCHEMBL256670 | 0.84 | — | — | |
| SCHEMBL16799829 | 0.79 | — | — | |
| SCHEMBL256032 | 0.77 | — | — | |
| SCHEMBL2128026 | 0.77 | — | — | |
| SCHEMBL27787478 | 0.77 | TDP1 (0.33) | ALDH1A1MAPTTDP1HSD11B1 | |
| SCHEMBL1229066 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4EPKMALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767120-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS; TREATMENT FOR SEPTIC SHOCK | SCHERING CORPORATION (US) | 1998-06-16 | — | — | US | disclosed |