Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719221 | 1.00 | PNMT (0.43) | PNMTMAPTGAALMNATSHR | |
| SCHEMBL8715309 | 0.87 | MEN1 (0.40) | MC4RAKR1C3AKR1C2 | |
| SCHEMBL8715306 | 0.87 | MEN1 (0.40) | MC4RAKR1C3AKR1C2 | |
| SCHEMBL8718504 | 0.85 | PNMT (0.46) | PNMTHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL8718507 | 0.85 | PNMT (0.46) | PNMTHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL8713278 | 0.84 | PNMT (0.45) | PNMTHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL8713281 | 0.84 | PNMT (0.45) | PNMTHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL8717141 | 0.84 | AOC3 (0.39) | GAASMN1; SMN2 | |
| SCHEMBL8717142 | 0.84 | AOC3 (0.39) | GAASMN1; SMN2 | |
| SCHEMBL8715549 | 0.83 | SMN1; SMN2 (0.51) | PNMTMAPTLMNASMN1; SMN2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |