Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713278 | 1.00 | PNMT (0.45) | PNMTHTR2AHTR2CHTR2BTP53 | |
| SCHEMBL8718504 | 0.87 | PNMT (0.46) | PNMTHTR2AHTR2CHTR2BACP3 | |
| SCHEMBL8718507 | 0.87 | PNMT (0.46) | PNMTHTR2AHTR2CHTR2BACP3 | |
| SCHEMBL8716351 | 0.87 | GRIN2B (0.44) | HTR2AHTR2CHTR2BTP53PDE2A | |
| SCHEMBL8716354 | 0.87 | GRIN2B (0.44) | HTR2AHTR2CHTR2BTP53PDE2A | |
| SCHEMBL8719221 | 0.84 | PNMT (0.43) | PNMTHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL8719224 | 0.84 | PNMT (0.43) | PNMTHTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL8719067 | 0.84 | HDAC8 (0.43) | PNMTHTR2AHTR2BCYP3A4CYP2C9 | |
| SCHEMBL8719065 | 0.84 | HDAC8 (0.43) | PNMTHTR2AHTR2BCYP3A4CYP2C9 | |
| SCHEMBL8713648 | 0.83 | SLC6A2 (0.39) | HTR2AHTR2BCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |