SCHEMBL8719231

SCHEMBL8719231

O=C1CC=C2OCOc3ccccc3/C=C\2C1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.37
ALOX5 P09917 1/20 0.35
NISCH Q9Y2I1 1/20 0.34
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7471966 0.73 PKM (0.38) PKMTSHRABCG2
SCHEMBL11810859 0.70 ABCG2 (0.39) PKMTSHRABCG2ALOX5NISCH
SCHEMBL4424499 0.60
SCHEMBL8711 0.60
SCHEMBL14417491 0.60 ABCG2 (1.00) PKMTSHRABCG2
SCHEMBL29353984 0.60
SCHEMBL7959398 0.58 CFTR (0.48)
SCHEMBL29518399 0.58 NISCH (0.53) ALOX5NISCH
SCHEMBL230113 0.58 NISCH (0.53) ALOX5NISCH
Formaldehyde SCHEMBL27287668 0.58 ABCG2 (0.82) PKMTSHRABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0851865-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 1998-07-08 EP disclosed
WO-1997011071-A1 NOVEL HETEROCYCLIC COMPOUNDS NOVO NORDISK A/S (DK) 1997-03-27 WO disclosed