Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29518399 | 1.00 | NISCH (0.53) | NISCHALOX5NPC1RAB9AMAPT | |
| SCHEMBL26549421 | 0.85 | NISCH (0.48) | NISCHALOX5NPC1RAB9AMAPT | |
| SCHEMBL28660144 | 0.85 | MAPT (0.50) | NISCHALOX5NPC1RAB9AMAPT | |
| SCHEMBL28660162 | 0.85 | PTGS1 (0.48) | NISCHALOX5NPC1RAB9AMAPT | |
| SCHEMBL26053155 | 0.84 | NISCH (0.40) | NISCHALOX5NPC1RAB9AMAPT | |
| SCHEMBL616344 | 0.80 | RARA (0.46) | NISCHALOX5RAB9AMAPTALDH1A1 | |
| SCHEMBL571115 | 0.79 | MAPT (0.45) | NISCHALOX5NPC1RAB9AMAPT | |
| SCHEMBL28672526 | 0.79 | ALOX5 (0.46) | NISCHALOX5MAPTALDH1A1LMNA | |
| SCHEMBL11230728 | 0.79 | LMNA (0.44) | NISCHALOX5NPC1RAB9AMAPT | |
| SCHEMBL30667714 | 0.78 | TLR2 (0.55) | NISCHNPC1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699218-B1 | USE OF A COMBINATION OF CAROTENOID, PHYTOESTROGEN AND VITAMIN C FOR THE PREVENTION AND/OR TREATMENT OF PIGMENTATION DISORDERS | NUTRICOS TECH (FR) | 2018-10-17 | — | — | EP | claimed |
| EP-2900336-B1 | ORAL COMPOSITION FOR REINFORCING SKIN TOLERANCE FOLLOWING TOPICAL ADMINISTRATION OF A RETINOID COMPOUND | NUTRICOS TECH (FR) | 2018-07-25 | — | — | EP | claimed |
| US-10022315-B2 | Oral composition for reinforcing skin tolerance following topical administration of a retinoid compound | LABORATOIRES INNEOV (FR) | 2018-07-17 | — | — | US | claimed |
| CN-103641808-B | The enantioselective hydrogenation method of chromene | GIRINDUS AMERICA INC. (US) | 2016-04-20 | — | — | CN | claimed |
| CN-103755675-B | The enantioselective hydrogenation method of chromene | GIRINDUS AMERICA INC. (US) | 2015-11-18 | — | — | CN | claimed |
| US-20150258000-A1 | ORAL COMPOSITION FOR REINFORCING SKIN TOLERANCE FOLLOWING TOPICAL ADMINISTRATION OF A RETINOID COMPOUND | LABORATORIES INNEOV (FR) | 2015-09-17 | — | — | US | claimed |
| EP-1919887-B1 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES | GIRINDUS AMERICA INC (US) | 2015-02-18 | — | — | EP | claimed |
| US-20140148401-A1 | COMBINATION OF CAROTENOID, PHYTOOESTROGEN AND VITAMIN C FOR MOISTURIZING THE SKIN | LABORATOIRES INNEOV (FR) | 2014-05-29 | — | — | US | claimed |
| CN-101535286-B | Process for the enantioselective hydrogenation of chromenes | GIRINDUS AMERICA INC | 2014-05-07 | — | — | CN | claimed |
| US-8716497-B2 | Method for enantioselective hydrogenation of chromenes | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2014-05-06 | — | — | US | claimed |
| US-7960573-B2 | Method for enantioselective hydrogenation of chromenes | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2011-06-14 | — | — | US | claimed |
| US-20100069653-A1 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES | Children hospital medical center (US) | 2010-03-18 | — | — | US | claimed |
| CN-101535286-A | Process for the enantioselective hydrogenation of chromenes | GIRINDUS AMERICA INC (US) | 2009-09-16 | — | — | CN | claimed |
| US-7528267-B2 | Method for enantioselective hydrogenation of chromenes | GIRINDUS AMERICA, INC. (US) | 2009-05-05 | — | — | US | claimed |
| US-20090105330-A1 | ADMIXTURE OF CAROTENOIDS AND ISOFLAVONOIDS FOR TREATING CUTANEOUS SYMPTOMS OF AGING | L'OREAL (FR) | 2009-04-23 | — | — | US | claimed |
| EP-1919887-A2 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES | Girindus America, Inc. (US) | 2008-05-14 | — | — | EP | claimed |
| WO-2007016423-A2 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES | GIRINDUS AMERICA INC. (US) | 2007-02-08 | — | — | WO | claimed |
| US-20070027329-A1 | Method for enantioselective hydrogenation of chromenes | AUSIO PHARMACEUTICALS, LLC | 2007-02-01 | — | — | US | claimed |
| US-20040071745-A1 | Admixture of carotenoids and isoflavonoids for treating cutaneous symptoms of aging | SOCIETE L'OREAL S.A. (FR) | 2004-04-15 | — | — | US | claimed |
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | L'OREAL (FR) | 2002-12-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020197289-A1 | Compositions and methods for combating the appearance of ageing | CYP24A1, CYP27B1, CYP2R1 | NISCH 1023/4885ALOX5 399/4885NPC1 4444/4885 |
| US-20070027329-A1 | Method for enantioselective hydrogenation of chromenes | HRH3, HRH2, CHD8 | NISCH 1832/4885ALOX5 1095/4885NPC1 4761/4885 |
| US-20100069653-A1 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES | HRH3, HRH2, CHD8 | NISCH 1832/4885ALOX5 1095/4885NPC1 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.