Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724174 | 0.92 | POLB (0.42) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8722456 | 0.83 | RAD52 (0.37) | POLBMAPTALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL8719317 | 0.82 | RAD52 (0.36) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8722985 | 0.82 | S1PR1 (0.43) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8722938 | 0.81 | AAK1 (0.40) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8930541 | 0.72 | MAPT (0.33) | POLBMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL8724171 | 0.72 | RAD52 (0.34) | POLBMAPTALDH1A1 | |
| SCHEMBL4581605 | 0.72 | MAPT (0.42) | POLBMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL4581596 | 0.70 | SLC6A9 (0.39) | MAPTALDH1A1LMNA | |
| SCHEMBL4581496 | 0.69 | MAPT (0.42) | POLBMAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814849-A1 | MAGNETICALLY LABELED CHEMOATTRACTANTS AS TARGETED CONTRAST AGENTS IN THE NMR IMAGING OF LIVING TISSUES | BRACCO International B.V. (NL) | 1998-01-07 | — | — | EP | disclosed |