Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719295 | 0.92 | POLB (0.47) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8724171 | 0.80 | RAD52 (0.34) | POLBMAPTALDH1A1 | |
| SCHEMBL8722456 | 0.79 | RAD52 (0.37) | POLBMAPTALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL8719317 | 0.78 | RAD52 (0.36) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8722985 | 0.77 | S1PR1 (0.43) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8722938 | 0.76 | AAK1 (0.40) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8724498 | 0.70 | RAD52 (0.36) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4581605 | 0.68 | MAPT (0.42) | POLBMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8930541 | 0.66 | MAPT (0.33) | POLBMAPTALDH1A1LMNANPC1 | |
| SCHEMBL4581596 | 0.65 | SLC6A9 (0.39) | MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814849-A1 | MAGNETICALLY LABELED CHEMOATTRACTANTS AS TARGETED CONTRAST AGENTS IN THE NMR IMAGING OF LIVING TISSUES | BRACCO International B.V. (NL) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997014443-A1 | MAGNETICALLY LABELED CHEMOATTRACTANTS AS TARGETED CONTRAST AGENTS IN THE NMR IMAGING OF LIVING TISSUES | BRACCO INTERNATIONAL B.V. (NL) | 1997-04-24 | — | — | WO | disclosed |