Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570426 | 0.89 | ALDH1A1 (0.64) | USP2CYP3A4CYP2C19CYP1A2CYP2C9 | |
| Hydrogen Peroxide SCHEMBL8527081 | 0.79 | ALDH1A1 (0.82) | USP2GAACFTRALDH1A1MEN1 | |
| SCHEMBL13656117 | 0.78 | ALDH1A1 (0.52) | USP2CYP3A4CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL9009717 | 0.78 | USP2 (1.00) | USP2CYP2C9GAACFTRALDH1A1 | |
| SCHEMBL3504943 | 0.77 | GAA (0.60) | USP2CYP3A4CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL3410872 | 0.77 | GAA (0.67) | USP2GAACFTRALDH1A1MEN1 | |
| SCHEMBL17537488 | 0.77 | CFTR (0.73) | USP2CYP3A4CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL17488976 | 0.77 | CFTR (0.73) | USP2CYP3A4CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL4401126 | 0.76 | GAA (0.59) | USP2CYP3A4CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL5836386 | 0.76 | ALDH1A1 (0.50) | USP2CYP3A4CYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789138-A | Optical recording medium and method of producing the same | RICOH COMPANY, LTD. (JP) | 1998-08-04 | — | — | US | disclosed |