Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719377 | 0.77 | ALDH1A1 (0.40) | KDM4EALDH1A1USP2ALOX15POLB | |
| SCHEMBL15834423 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1USP2ALOX15POLB | |
| SCHEMBL5557273 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1USP2ALOX15POLB | |
| SCHEMBL13541637 | 0.75 | ALDH1A1 (0.53) | KDM4EALDH1A1USP2ALOX15POLB | |
| SCHEMBL5551506 | 0.74 | ALDH1A1 (0.46) | KDM4EALDH1A1USP2ALOX15POLB | |
| SCHEMBL9615184 | 0.74 | ALDH1A1 (0.52) | KDM4EALDH1A1USP2ALOX15POLB | |
| SCHEMBL7171466 | 0.74 | KMT2A (0.54) | SMN1; SMN2MAPK1L3MBTL1MAPTABCB1 | |
| SCHEMBL12605180 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1USP2ALOX15POLB | |
| SCHEMBL5555195 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1USP2ALOX15POLB | |
| SCHEMBL12650479 | 0.73 | ALDH1A1 (0.45) | KDM4EALDH1A1USP2ALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512661-B1 | Macrocyclic polymer-complexing, their complexes, method for their production and pharmaceutical agents containing them | SCHERING AG (DE) | 1998-01-14 | — | — | EP | disclosed |
| EP-0512661-A1 | Macrocyclic polymer-complexing, their complexes, method for their production and pharmaceutical agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |