Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5557277 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL8560245 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL5551517 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL5555201 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL8481805 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL5551332 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL8719375 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL5555297 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL5555359 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL8559141 | 0.75 | ALDH1A1 (0.52) | ALDH1A1KDM4EUSP2ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512661-B1 | Macrocyclic polymer-complexing, their complexes, method for their production and pharmaceutical agents containing them | SCHERING AG (DE) | 1998-01-14 | — | — | EP | disclosed |
| EP-0512661-A1 | Macrocyclic polymer-complexing, their complexes, method for their production and pharmaceutical agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |