Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719455 | 1.00 | PSIP1 (0.49) | PSIP1KDM4AKDM4BKDM5BLMNA | |
| SCHEMBL6250244 | 0.85 | ALDH1A1 (0.52) | KDM4AKDM4BKDM5BSMN1; SMN2ALDH1A1 | |
| SCHEMBL6250250 | 0.85 | ALDH1A1 (0.52) | KDM4AKDM4BKDM5BSMN1; SMN2ALDH1A1 | |
| SCHEMBL35184 | 0.79 | CYP2C19 (0.55) | PSIP1LMNAALDH1A1CYP2C19MAPT | |
| SCHEMBL29453097 | 0.79 | CYP2C19 (0.55) | PSIP1LMNAALDH1A1CYP2C19MAPT | |
| SCHEMBL27961684 | 0.77 | PSIP1 (0.52) | PSIP1KDM4AKDM4BKDM5BLMNA | |
| SCHEMBL27542620 | 0.77 | PSIP1 (0.44) | PSIP1KDM4AKDM4BKDM5BLMNA | |
| SCHEMBL29113953 | 0.75 | CES1 (0.50) | LMNASMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL14590999 | 0.75 | CES1 (0.50) | LMNASMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL8719447 | 0.75 | TSHR (0.43) | PSIP1LMNASMN1; SMN2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733909-A | ANTIINFLAMMATORY AGENTS; ANALGESICS; ANTIPYRETIC AGENT | MERCK FROSST CANADA, INC. (CA) | 1998-03-31 | — | — | US | disclosed |