SCHEMBL8719631

SCHEMBL8719631

C=CCc1ccc(-c2ccc(CCCC(C)O)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 3/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
ALOX12 P18054 1/20 0.40
PTGS2 P35354 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALOX5 P09917 2/20 0.37
XDH P47989 1/20 0.36
FDFT1 P37268 3/20 0.36
MEN1 O00255 3/20 0.35
GAA P10253 3/20 0.35
MAPT P10636 3/20 0.35
KMT2A Q03164 3/20 0.35
KDM4E B2RXH2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8721477 0.95 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8719510 0.94 RARB (0.38) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8719622 0.94 RARB (0.38) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8716923 0.90 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL5695986 0.84 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL9241709 0.81 GRIN2D (0.47) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8047719 0.80 PTGS2 (0.34) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8047718 0.80 PTGS2 (0.34) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8036885 0.80 PTGS2 (0.34) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8036884 0.80 PTGS2 (0.34) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5741438-A Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as an effective component, and liquid crystal element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-21 US disclosed