Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807780 | 0.98 | HDAC2 (0.50) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL8716910 | 0.98 | HDAC2 (0.50) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL8716921 | 0.98 | HDAC2 (0.50) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL8719636 | 0.95 | FDFT1 (0.54) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL560219 | 0.89 | TRPA1 (0.51) | ALDH1A1CYP2D6 | |
| SCHEMBL10473806 | 0.89 | TRPA1 (0.51) | ALDH1A1CYP2D6 | |
| SCHEMBL16058107 | 0.89 | TRPA1 (0.51) | ALDH1A1CYP2D6 | |
| SCHEMBL425971 | 0.87 | MMP12 (0.59) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL4590802 | 0.87 | TRPA1 (0.54) | — | |
| SCHEMBL10037075 | 0.87 | TRPA1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741438-A | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as an effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-21 | — | — | US | disclosed |
| EP-0395390-B1 | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL CO (JP) | 1994-09-28 | — | — | EP | disclosed |
| EP-0395390-A1 | Optically active biphenyl derivative, process for preparation thereof, liquid crystal composition containing the same as effective component, and liquid crystal element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-3950427-A | ANTIINFLAMMATORY, ANTIPYRETIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |