SCHEMBL871965

SCHEMBL871965

COC1=C(OC)C(=O)C(C)=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 2/20 0.36
CDC25B P30305 2/20 0.36
MAPT P10636 6/20 0.35
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
RAB9A P51151 3/20 0.35
LMNA P02545 2/20 0.35
POLB P06746 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAP2K7 O14733 1/20 0.35
GMNN O75496 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18622284 0.66
SCHEMBL11761594 0.64
SCHEMBL9655485 0.63 CDC25A (0.64) CDC25ACDC25BMAPTALDH1A1KDM4E
SCHEMBL5590298 0.63 CDC25A (0.56) CDC25ACDC25BMAPTALDH1A1KDM4E
Ubiquinone Qo SCHEMBL49420 0.62 HKDC1 (0.61) CDC25ACDC25BMAPTALDH1A1KDM4E
SCHEMBL14894669 0.61 ALDH1A1 (0.50) CDC25ACDC25BMAPTALDH1A1KDM4E
SCHEMBL783100 0.60
Ubiquinone Qo SCHEMBL29631791 0.60 HKDC1 (0.47) CDC25ACDC25BMAPTALDH1A1KDM4E
SCHEMBL12592463 0.59 CDC25A (0.58) CDC25ACDC25BMAPTALDH1A1KDM4E
SCHEMBL3420496 0.59 MAPT (0.58) CDC25ACDC25BMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4146180-A1 METHODS AND COMPOSITIONS FOR TREATING AN RNA VIRUS INDUCED DISEASE Golden Biotechnology Corporation (US) 2023-03-15 EP disclosed
WO-2021226412-A1 METHODS AND COMPOSITIONS FOR TREATING AN RNA VIRUS INDUCED DISEASE GOLDEN BIOTECHNOLOGY CORPORATION (US) 2021-11-11 WO disclosed
EP-3541777-A1 METHODS AND COMPOSITIONS FOR TREATING ATOPIC DERMATITIS Golden Biotechnology Corporation (US) 2019-09-25 EP disclosed
WO-2018094122-A1 METHODS AND COMPOSITIONS FOR TREATING ATOPIC DERMATITIS GOLDEN BIOTECHNOLOGY CORPORATION (US) 2018-05-24 WO disclosed
WO-2014151304-A1 THERAPEUTIC METHODS AND COMPOSITIONS UTILIZING CYCLOHEXENONE COMPOUNDS GOLDEN BIOTECHNOLOGY CORPORATION (US) 2014-09-25 WO disclosed
EP-2655309-A1 METHODS AND COMPOSITIONS FOR TREATING LUNG CANCER Golden Biotechnology Corporation (US) 2013-10-30 EP disclosed
WO-2012039793-A1 METHODS AND COMPOSITIONS FOR TREATING LUNG CANCER GOLDEN BIOTECHNOLOGY CORPORATION (US) 2012-03-29 WO disclosed