Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717107 | 0.92 | GAA (0.45) | CCKBRGAAALDH1A1F2MEN1 | |
| SCHEMBL8686247 | 0.91 | CCKBR (0.50) | CCKBRALDH1A1F2 | |
| SCHEMBL8716958 | 0.90 | CCKBR (0.45) | CCKBRGAAALDH1A1F2MEN1 | |
| SCHEMBL8685939 | 0.88 | CCKBR (0.54) | CCKBRALDH1A1F2 | |
| SCHEMBL8690382 | 0.88 | CCKBR (0.54) | CCKBRALDH1A1F2 | |
| SCHEMBL8716935 | 0.82 | GAA (0.46) | GAAALDH1A1F2MEN1KMT2A | |
| SCHEMBL7327272 | 0.82 | GAA (0.42) | GAAALDH1A1F2MEN1KMT2A | |
| SCHEMBL8716462 | 0.82 | GAA (0.49) | GAAALDH1A1F2MEN1KMT2A | |
| SCHEMBL8684060 | 0.80 | F2 (0.48) | ALDH1A1F2PLG | |
| SCHEMBL8721707 | 0.79 | GAA (0.47) | GAAALDH1A1F2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |