Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685939 | 1.00 | CCKBR (0.54) | CCKBRF2ALDH1A1MMP1MMP7 | |
| SCHEMBL8686247 | 0.97 | CCKBR (0.50) | CCKBRF2ALDH1A1MMP1MMP7 | |
| SCHEMBL8716958 | 0.90 | CCKBR (0.45) | CCKBRF2ALDH1A1 | |
| SCHEMBL8719933 | 0.88 | CCKBR (0.45) | CCKBRF2ALDH1A1 | |
| SCHEMBL8717107 | 0.87 | GAA (0.45) | CCKBRF2ALDH1A1MMP1MMP7 | |
| SCHEMBL8684060 | 0.85 | F2 (0.48) | F2ALDH1A1MMP1MMP7ACE | |
| SCHEMBL8685892 | 0.81 | CCKBR (0.48) | CCKBRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8947697 | 0.81 | MMP13 (0.51) | F2ALDH1A1MMP1MMP7ACE | |
| SCHEMBL8690613 | 0.80 | SLC1A3 (0.49) | CCKBRF2MMP13SLC1A3SLC1A2 | |
| SCHEMBL8684043 | 0.80 | F2 (0.43) | CCKBRF2ALDH1A1MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847125-A | Amino acid derivatives with anticholecystokinin activity | JAMES BLACK FOUNDATION LIMITED (GB) | 1998-12-08 | — | — | US | disclosed |
| EP-0625141-B1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY | BLACK JAMES FOUNDATION (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0625141-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY. | BLACK JAMES FOUNDATION (GB) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993014066-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY | JAMES BLACK FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |