Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717293 | 0.84 | GAA (0.35) | GAAMAPTIDO1L3MBTL1LATS1 | |
| SCHEMBL8717871 | 0.83 | GAA (0.35) | GAAMAPTIDO1L3MBTL1LATS1 | |
| SCHEMBL8720094 | 0.78 | L3MBTL1 (0.38) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL7066158 | 0.77 | LATS1 (0.39) | GAAMAPTIDO1L3MBTL1LATS1 | |
| SCHEMBL7067988 | 0.76 | GAA (0.44) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL7067970 | 0.76 | GAA (0.36) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL8720104 | 0.75 | GAA (0.42) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL7069716 | 0.75 | KDM4C (0.43) | GAAMAPTIDO1L3MBTL1LATS1 | |
| SCHEMBL7068588 | 0.75 | KDM4C (0.43) | GAAMAPTIDO1L3MBTL1LATS1 | |
| SCHEMBL7068593 | 0.75 | KDM4C (0.43) | GAAMAPTIDO1L3MBTL1LATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877748-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997026264-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |