Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720260 | 1.00 | EGFR (0.56) | EGFRHDAC3EP300TUBB4ATUBB | |
| SCHEMBL1170385 | 0.94 | HDAC3 (0.51) | EGFRHDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL1898585 | 0.88 | NPC1 (0.50) | EGFRHDAC3TDP1NPC1L3MBTL1 | |
| Styrene SCHEMBL925987 | 0.87 | HDAC3 (0.46) | EGFRHDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL11043779 | 0.85 | HAO1 (0.44) | EGFRHDAC3TDP1NPC1L3MBTL1 | |
| SCHEMBL9246692 | 0.85 | HDAC3 (0.47) | EGFRHDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL3799708 | 0.81 | GLA (0.53) | EGFRHDAC3TDP1NPC1L3MBTL1 | |
| Cinnamic Acid SCHEMBL28752126 | 0.79 | HDAC3 (0.70) | EGFRHDAC3TUBB4ATUBBTUBA3C | |
| SCHEMBL3175778 | 0.77 | MAPT (0.55) | EGFRHDAC3TDP1NPC1L3MBTL1 | |
| SCHEMBL3175772 | 0.77 | MAPT (0.55) | EGFRHDAC3TDP1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998030318-A2 | COMPOUNDS FOR PRODUCING NANOPOROUS POLYMERS, NANOCOMPOSITE AND MEMBRANES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-16 | — | — | WO | disclosed |