Styrene

Styrene

SCHEMBL925987

C=Cc1ccccc1.CCCCC=C(C=Cc1ccccc1)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.46
EGFR P00533 1/20 0.46
NPC1 O15118 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
GLA P06280 1/20 0.41
HAO1 Q9UJM8 1/20 0.41
LMNA P02545 3/20 0.40
ALDH1A1 P00352 3/20 0.40
TNKS O95271 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1170385 0.93 HDAC3 (0.51) HDAC3EGFRNPC1L3MBTL1TDP1
Styrene SCHEMBL8470304 0.89 ALDH1A1 (0.38) HDAC3EGFRTDP1LMNAALDH1A1
SCHEMBL8720260 0.87 EGFR (0.56) HDAC3EGFRNPC1L3MBTL1TDP1
SCHEMBL8720263 0.87 EGFR (0.56) HDAC3EGFRNPC1L3MBTL1TDP1
SCHEMBL9246692 0.87 HDAC3 (0.47) HDAC3EGFRNPC1L3MBTL1TDP1
SCHEMBL1898585 0.84 NPC1 (0.50) HDAC3EGFRNPC1L3MBTL1TDP1
Styrene SCHEMBL9149703 0.84 TDP1 (0.36) HDAC3EGFRNPC1L3MBTL1TDP1
Styrene SCHEMBL3170624 0.81 EP300 (0.54) HDAC3EGFRTDP1LMNAALDH1A1
Styrene SCHEMBL3141180 0.80 AKR1C3 (0.46) HDAC3EGFRTDP1GLALMNA
Styrene SCHEMBL393960 0.80 AKR1C3 (0.46) HDAC3EGFRTDP1GLALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8013051-B2 Wear resistance of coloring material; mixture of liquid organosilicon polymer and polystyrene CANON KABUSHIKI KAISHA (JP) 2011-09-06 US disclosed
US-7918928-B2 Accuracy; storage stability; wear resistance; mixture of pigment, organosilicon compound and polymer CANON KABUSHIKI KAISHA (JP) 2011-04-05 US disclosed
US-7868060-B2 Aqueous ink, ink jet recording method, ink cartridge, recording unit, ink jet recording apparatus, and image CANON KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed