SCHEMBL3799708

SCHEMBL3799708

CCC=C(C=Cc1ccccc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
NPC1 O15118 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 3/20 0.52
ALDH1A1 P00352 3/20 0.52
HDAC3 O15379 3/20 0.52
HDAC4 P56524 2/20 0.52
HDAC1 Q13547 2/20 0.52
HDAC2 Q92769 2/20 0.52
HDAC8 Q9BY41 2/20 0.52
HDAC6 Q9UBN7 2/20 0.52
PLIN1 O60240 2/20 0.52
MAPT P10636 2/20 0.52
RECQL P46063 2/20 0.52
PLIN5 Q00G26 2/20 0.52
ABHD5 Q8WTS1 2/20 0.52
TNKS O95271 1/20 0.52
HCAR2 Q8TDS4 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1898585 0.86 NPC1 (0.50) GLATDP1NPC1L3MBTL1LMNA
SCHEMBL3175778 0.85 MAPT (0.55) GLATDP1NPC1L3MBTL1LMNA
SCHEMBL3175772 0.85 MAPT (0.55) GLATDP1NPC1L3MBTL1LMNA
SCHEMBL1170385 0.83 HDAC3 (0.51) GLATDP1NPC1L3MBTL1LMNA
SCHEMBL1172618 0.81 EGFR (0.49) GLATDP1NPC1L3MBTL1LMNA
SCHEMBL8720263 0.81 EGFR (0.56) GLATDP1NPC1L3MBTL1LMNA
SCHEMBL8720260 0.81 EGFR (0.56) GLATDP1NPC1L3MBTL1LMNA
SCHEMBL1170392 0.81 TDP1 (0.61) GLATDP1NPC1L3MBTL1LMNA
SCHEMBL8418896 0.79 NPC1 (0.50) GLATDP1NPC1L3MBTL1LMNA
Styrene SCHEMBL925987 0.78 HDAC3 (0.46) GLATDP1NPC1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7858281-B2 Acid-base property considerations for improved additive attachment on toner XEROX CORPORATION (US) 2010-12-28 US disclosed
US-20090130588-A1 ACID-BASE PROPERTY CONSIDERATIONS FOR IMPROVED ADDITIVE ATTACHEMENT ON TONER XEROX CORPORATION (US) 2009-05-21 US disclosed
WO-2003028994-A1 WALL COVERING COMPRISING A VENEER TOP LAYER DECOSPAN N.V. (BE) 2003-04-10 WO disclosed
EP-0360128-A1 Compatible polymer composition RÖHM GMBH (DE) 1990-03-28 EP disclosed