Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18459257 | 0.81 | ACACB (0.49) | ACACBCYP1A2CYP2D6TAAR1SIGMAR1 | |
| SCHEMBL18459318 | 0.81 | ACACB (0.49) | ACACBCYP1A2CYP2D6TAAR1SIGMAR1 | |
| SCHEMBL10076448 | 0.80 | TAAR1 (0.65) | ACACBCYP2D6TAAR1SIGMAR1SLC18A2 | |
| SCHEMBL178625 | 0.80 | TAAR1 (0.65) | ACACBCYP2D6TAAR1SIGMAR1SLC18A2 | |
| SCHEMBL11409619 | 0.80 | AGXT (0.46) | ACACBCYP1A2TAAR1CYP2A6SLC6A4 | |
| Pheniprazine SCHEMBL28842219 | 0.80 | SIGMAR1 (0.65) | CYP1A2CYP2D6TAAR1SIGMAR1SLC18A2 | |
| Pheniprazine SCHEMBL13063297 | 0.80 | SIGMAR1 (0.65) | CYP1A2CYP2D6TAAR1SIGMAR1SLC18A2 | |
| Pheniprazine SCHEMBL163709 | 0.80 | SIGMAR1 (0.65) | CYP1A2CYP2D6TAAR1SIGMAR1SLC18A2 | |
| Hydrochloric Acid SCHEMBL7343144 | 0.79 | SLC6A2 (0.59) | ACACBCYP1A2CYP2D6TAAR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL23524368 | 0.78 | TAAR1 (0.63) | ACACBCYP2D6TAAR1SIGMAR1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868420-A1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI (FR) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997021682-A1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI (FR) | 1997-06-19 | — | — | WO | disclosed |