Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.65 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.65 |
| ▸ | GRIN2D | O15399 | 7/20 | 0.65 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.65 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.65 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.65 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | STAT6 | P42226 | 1/20 | 0.65 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132159 | 1.00 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL510762 | 1.00 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL9914296 | 1.00 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL12130587 | 1.00 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Water SCHEMBL28015899 | 0.97 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Hydrochloric Acid SCHEMBL1880961 | 0.97 | LMNA (0.67) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Hydrochloric Acid SCHEMBL866896 | 0.97 | LMNA (0.67) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL1362423 | 0.85 | PKM (0.56) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Amantadine SCHEMBL4846924 | 0.84 | GRIN1 (0.81) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL18543598 | 0.81 | PKM (0.95) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998034646-A2 | TARGETED ANTIOXIDANTS | UNIVERSITY OF HERTFORDSHIRE (GB) | 1998-08-13 | — | — | WO | disclosed |