Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.36 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718085 | 0.83 | CNR2 (0.33) | CNR2BCHECNR1OPRM1OPRD1 | |
| SCHEMBL8714480 | 0.82 | SLC18A2 (0.35) | CNR2BCHECNR1OPRM1OPRD1 | |
| SCHEMBL8718081 | 0.78 | PIN1 (0.33) | CNR2CNR1OPRM1OPRD1OPRK1 | |
| SCHEMBL8715069 | 0.78 | HRH3 (0.35) | CNR2CNR1ACHEMEN1KMT2A | |
| SCHEMBL8714510 | 0.77 | PDE10A (0.39) | MAPTHCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL9241754 | 0.77 | EPHX1 (0.36) | OPRM1OPRD1OPRK1HCRTR1HCRTR2 | |
| SCHEMBL8716980 | 0.77 | EPHX1 (0.36) | OPRM1OPRD1OPRK1HCRTR1HCRTR2 | |
| SCHEMBL9244512 | 0.75 | CNR2 (0.37) | CNR2BCHECNR1OPRM1OPRD1 | |
| SCHEMBL9244509 | 0.75 | GAA (0.38) | OPRM1OPRD1OPRK1POLBMAPT | |
| SCHEMBL9244519 | 0.75 | GAA (0.38) | OPRM1OPRD1OPRK1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719291-A | FUNGICIDE | HOFFMANN-LA ROCHE INC. (US) | 1998-02-17 | — | — | US | disclosed |