Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717311 | 0.92 | PDE10A (0.36) | PDE10AHCRTR1HCRTR2 | |
| SCHEMBL8715055 | 0.86 | PDE10A (0.38) | PDE10AHCRTR1HCRTR2 | |
| SCHEMBL8713734 | 0.84 | PDE10A (0.39) | PDE10AHCRTR1HCRTR2MEN1MAPT | |
| SCHEMBL8714661 | 0.84 | PDE10A (0.36) | PDE10AHCRTR1HCRTR2 | |
| SCHEMBL9244570 | 0.80 | CYP1A2 (0.35) | PDE10AHCRTR1HCRTR2 | |
| SCHEMBL8719748 | 0.80 | CYP1A2 (0.35) | PDE10AHCRTR1HCRTR2 | |
| SCHEMBL8714654 | 0.79 | CYP1A2 (0.34) | PDE10AHCRTR1HCRTR2 | |
| SCHEMBL8720642 | 0.77 | CNR2 (0.36) | HCRTR1HCRTR2MEN1MAPTKMT2A | |
| SCHEMBL9243685 | 0.77 | CALCA (0.35) | PDE10AHCRTR1HCRTR2 | |
| SCHEMBL9245399 | 0.77 | REN (0.34) | PDE10AHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719291-A | FUNGICIDE | HOFFMANN-LA ROCHE INC. (US) | 1998-02-17 | — | — | US | disclosed |