Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156077 | 0.76 | APP (0.44) | ESR1ESR2LMNAHSD17B10TYR | |
| SCHEMBL14003947 | 0.71 | TYR (0.46) | ESR1ESR2LMNAHSD17B10TYR | |
| SCHEMBL8933146 | 0.70 | TYR (0.49) | ESR1ESR2LMNAHSD17B10TYR | |
| SCHEMBL8933393 | 0.70 | TYR (0.49) | ESR1ESR2LMNAHSD17B10TYR | |
| SCHEMBL14557525 | 0.70 | TYR (0.49) | ESR1ESR2LMNAHSD17B10TYR | |
| SCHEMBL8007165 | 0.70 | ALOX15 (0.38) | ESR1LMNAHSD17B10TYRALOX15 | |
| SCHEMBL8933167 | 0.70 | TYR (0.49) | ESR1ESR2LMNAHSD17B10TYR | |
| SCHEMBL8007169 | 0.70 | ALOX15 (0.38) | ESR1LMNAHSD17B10TYRALOX15 | |
| SCHEMBL14003948 | 0.69 | NAAA (0.36) | LMNAHSD17B10TYRALOX15ALDH1A1 | |
| SCHEMBL926861 | 0.68 | ALOX15 (0.48) | ESR1LMNAHSD17B10TYRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662004-B1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1998-03-18 | — | — | EP | disclosed |
| US-5700448-A | Use of persistent free-radicals in magnetic resonance imaging | NYCOMED IMAGING AS (NO) | 1997-12-23 | — | — | US | disclosed |
| US-5435991-A | Use of persistent heterocyclic free-radicals in magnetic resonance imaging | NYCOMED INNOVATION AB (SE) | 1995-07-25 | — | — | US | disclosed |
| EP-0662004-A1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | Nycomed Innovation AB (SE) | 1995-07-12 | — | — | EP | disclosed |
| WO-1993002710-A2 | USE OF PERSISTENT FREE RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1993-02-18 | — | — | WO | disclosed |
| WO-1993002711-A1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1993-02-18 | — | — | WO | disclosed |