Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 3/20 | 0.32 |
| ▸ | HTR1B | P28222 | 3/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 3/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383378 | 0.88 | DRD2 (0.37) | SLC6A4DRD2HTR2ADRD3MBTD1 | |
| SCHEMBL8386604 | 0.84 | SLC6A4 (0.46) | SLC6A4HSD11B1HTR1DHTR1BNOS1 | |
| SCHEMBL30908881 | 0.84 | SLC6A4 (0.46) | SLC6A4HSD11B1HTR1DHTR1BNOS1 | |
| SCHEMBL8724233 | 0.78 | SLC6A4 (0.43) | SLC6A4HSD11B1HTR1DHTR1BHTR1A | |
| SCHEMBL8721914 | 0.78 | SLC6A4 (0.39) | SLC6A4HSD11B1HTR1BHTR1A | |
| SCHEMBL30909176 | 0.75 | DRD2 (0.38) | SLC6A4DRD2HTR2ADRD3L3MBTL3 | |
| SCHEMBL8383620 | 0.75 | DRD2 (0.38) | SLC6A4DRD2HTR2ADRD3L3MBTL3 | |
| SCHEMBL8383095 | 0.74 | GAA (0.40) | DRD2HTR2ADRD3 | |
| SCHEMBL8386464 | 0.74 | HTR1D (0.53) | HTR1DHTR1BDRD2HTR1A | |
| SCHEMBL30909175 | 0.74 | HTR1D (0.53) | HTR1DHTR1BDRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |