Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058336 | 0.94 | IDO1 (0.58) | IDO1AKR1C3ALDH1A1MAOBTSHR | |
| SCHEMBL2058333 | 0.80 | IDO1 (0.61) | IDO1AKR1C3ALDH1A1MAOBTSHR | |
| Butane SCHEMBL8002745 | 0.80 | IDO1 (0.42) | IDO1ALDH1A1TSHRMEN1TP53 | |
| Butane SCHEMBL9443644 | 0.78 | APP (0.41) | ALDH1A1MAOBTSHRCYP1A2MAPT | |
| Butane SCHEMBL3196642 | 0.78 | AGXT (0.44) | IDO1ALDH1A1MAOBCYP1A2MAPT | |
| SCHEMBL7761382 | 0.78 | IDO1 (0.54) | IDO1AKR1C3ALDH1A1MAOBTSHR | |
| Butane SCHEMBL9160588 | 0.77 | ALDH1A1 (0.41) | AKR1C3ALDH1A1BCL9CTNNB1CYP1A2 | |
| Butane SCHEMBL6056712 | 0.77 | IDO1 (0.42) | IDO1ALDH1A1MAOBMAOA | |
| Butane SCHEMBL2802241 | 0.77 | POLB (0.42) | IDO1ALDH1A1MAOBMEN1MAPT | |
| Butane SCHEMBL1238313 | 0.76 | ALDH1A1 (0.46) | IDO1ALDH1A1MAOBTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801935-B | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2014-12-03 | — | — | CN | disclosed |
| CN-103608333-A | Androgen receptor antagonists and uses thereof | SUZHOU KINTOR PHARMACEUTICALS INC | 2014-02-26 | — | — | CN | disclosed |
| CN-103384664-A | Anti-viral compounds | ABBVIE INC | 2013-11-06 | — | — | CN | disclosed |
| CN-102746239-A | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2012-10-24 | — | — | CN | disclosed |
| CN-101208371-B | Method for preparing polyester and polyester manufactured by the method as well as polyester formed body | TOYO BOSEKI | 2011-08-10 | — | — | CN | disclosed |
| CN-101918369-A | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2010-12-15 | — | — | CN | disclosed |
| CN-101801935-A | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2010-08-11 | — | — | CN | disclosed |
| CN-101208371-A | Method for preparing polyester and polyester manufactured by the method as well as polyester formed body | TOYO BOSEKI (JP) | 2008-06-25 | — | — | CN | disclosed |
| EP-0868682-A1 | ELECTRO- OR OPTO-OPTICAL DEVICE STABLE IN THE 600-1600 NANOMETER WAVELENGTH RANGE | Akzo Nobel N.V. (NL) | 1998-10-07 | — | — | EP | disclosed |
| US-5776375-A | CONTAINING NONLINEAR OPTICALLY ACTIVE POLYMER | AKZO NOBEL N.V. (NL) | 1998-07-07 | — | — | US | disclosed |
| CN-1156849-A | Organosilicon-modified charge transporting compound and curable composition containing compound and having charge transporting ability | DOW CORNING ASIA LTD (JP) | 1997-08-13 | — | — | CN | disclosed |
| WO-1997023807-A1 | ELECTRO- OR OPTO-OPTICAL DEVICE STABLE IN THE 600-1600 NANOMETER WAVELENGTH RANGE | AKZO NOBEL N.V. (NL) | 1997-07-03 | — | — | WO | disclosed |
| EP-0780722-A1 | Electro-optical device stable in the 600-1600 nanometer wavelength range | Akzo Nobel N.V. (NL) | 1997-06-25 | — | — | EP | disclosed |
| US-5416112-A | Antiinflammatory agents | ROUSSEL UCLAF (FR) | 1995-05-16 | — | — | US | disclosed |
| US-5097022-A | Bisazo pigments for use in electrophotographic photoconductors | RICOH COMPANY, LTD. (JP) | 1992-03-17 | — | — | US | disclosed |