Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL8720911 | 0.94 | IDO1 (0.51) | IDO1AKR1C3TSHRLOXL2ALDH1A1 | |
| SCHEMBL2058333 | 0.85 | IDO1 (0.61) | IDO1AKR1C3TSHRLOXL2ALDH1A1 | |
| Methane SCHEMBL27339910 | 0.81 | TSHR (0.54) | IDO1AKR1C3TSHRLOXL2ALDH1A1 | |
| SCHEMBL27850481 | 0.80 | F2 (0.54) | TSHRALDH1A1MEN1MAPTALOX15 | |
| SCHEMBL7761382 | 0.79 | IDO1 (0.54) | IDO1AKR1C3TSHRLOXL2ALDH1A1 | |
| SCHEMBL6839686 | 0.77 | IDO1 (0.56) | IDO1AKR1C3TSHRLOXL2ALDH1A1 | |
| SCHEMBL7769668 | 0.77 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2ALDH1A1 | |
| SCHEMBL12417032 | 0.77 | IDO1 (0.66) | IDO1AKR1C3TSHRLOXL2ALDH1A1 | |
| SCHEMBL37463 | 0.77 | IDO1 (0.70) | IDO1AKR1C3TSHRLOXL2ALDH1A1 | |
| SCHEMBL8062311 | 0.77 | IDO1 (0.70) | IDO1AKR1C3TSHRLOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118339172-A | Phosphonic acid compounds and prodrugs thereof, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-11801315-B2 | Radioligands for myelin | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-10-31 | — | — | US | disclosed |
| EP-4259145-A1 | ALK-5 INHIBITORS AND USES THEREOF | Sumitomo Pharma Oncology, Inc. (US) | 2023-10-18 | — | — | EP | disclosed |
| US-11746103-B2 | ALK-5 inhibitors and uses thereof | SUMITOMO PHARMA ONCOLOGY, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| CN-116569083-A | Laminated film for liquid crystal polarizing film, surface protective film for liquid crystal polarizing film, laminate with liquid crystal polarizing film, and image display device comprising liquid crystal polarizing film | 三菱化学株式会社 | 2023-08-08 | — | — | CN | disclosed |
| CN-116546986-A | ALK-5 inhibitors and uses thereof | 住友制药肿瘤公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116547144-A | Adhesive composition for coated polarizing element, adhesive sheet for image display device constituent member, adhesive sheet with release film, adhesive sheet with image display device constituent member, laminate, coated polarizing element with adhesive layer, adhesive sheet with polarizing element, and image display device | 三菱化学株式会社 | 2023-08-04 | — | — | CN | disclosed |
| US-11697636-B2 | Substituted benzamides | HOFFMANN-LA ROCHE INC. (US) | 2023-07-11 | — | — | US | disclosed |
| US-20230201382-A1 | RADIOLIGANDS FOR MYELIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-06-29 | — | — | US | disclosed |
| CN-116034140-A | Compound, composition for anisotropic dye film comprising same, anisotropic dye film, and optical element | 三菱化学株式会社 | 2023-04-28 | — | — | CN | disclosed |
| US-6495673-B1 | EXPRESSION LIBRARY PRODUCED BY MUTAGENESIS | MEDICAL RESEARCH COUNCIL (GB) | 2002-12-17 | — | — | US | disclosed |
| US-6184012-B1 | LINKING ENZYME TO SUBSTRATE FOR THAT ENZYME, REACTING TO PRODUCE PRODUCT WHICH IS STILL LINKED TO ENZYME, THEN ISOLATING ENZYME BY SELECTIVELY ISOLATING PRODUCT | MEDICAL RESEARCH COUNCIL (GB) | 2001-02-06 | — | — | US | disclosed |
| EP-0895536-A2 | ISOLATION OF ENZYMES | MEDICAL RESEARCH COUNCIL (GB) | 1999-02-10 | — | — | EP | disclosed |
| US-5858296-A | A BIOLOGICALLY ACTIVE MOLECULE FORMED BY POLYMERIZATION OF FUNCTIONAL MONOMERS AROUND A TEMPLATE MOLECULE THAT EXHIBITS DRUG ACTIVITY, REMOVAL OF TEMPLATE AND POLYMERIZATION OF SECOND CLASS OF MONOMER IN THE VOIDS LEFT BY TEMPLATE | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1999-01-12 | — | — | US | disclosed |
| WO-1997040141-A2 | ISOLATION OF ENZYMES | MEDICAL RESEARCH COUNCIL (GB) | 1997-10-30 | — | — | WO | disclosed |
| US-5630978-A | POLYMERIZATION OF FUNCTIONAL MONOMERS AROUND A BIOLOGICALLY ACTIVE TEMPLATE MOLECULE, REMOVAL OF TEMPLATE TO LEAVE A VOID, THEN POLYMERIZATION OF OTHER MONOMER(S) IN THE VOID | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1997-05-20 | — | — | US | disclosed |
| WO-1996040822-A1 | PREPARATION OF BIOLOGICALLY ACTIVE MOLECULES BY MOLECULAR IMPRINTING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5520710-A | Cleaner burning and cetane enhancing diesel fuel supplements | Olah, George A. (US) | 1996-05-28 | — | — | US | disclosed |
| US-5486559-A | CHARGE TRANSFER ABSORPTION BAND FOR DOPANTS | AKZO NOBEL NV (NL) | 1996-01-23 | — | — | US | disclosed |
| EP-0639786-A1 | Optically non-linear active waveguiding material comprising donor and acceptor groups-containing triphenylcarbinols | Akzo Nobel N.V. (NL) | 1995-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230201382-A1 | RADIOLIGANDS FOR MYELIN | MAG, PMP22, MYT1 | IDO1 2596/4885AKR1C3 3401/4885TSHR 721/4885 |
| US-11801315-B2 | Radioligands for myelin | MAG, PMP22, MYT1 | IDO1 3999/4885AKR1C3 4400/4885TSHR 275/4885 |
| US-11697636-B2 | Substituted benzamides | TAAR1, TAAR5, NPY1R | IDO1 554/4885AKR1C3 515/4885TSHR 15/4885 |
| US-11746103-B2 | ALK-5 inhibitors and uses thereof | ACVR1, ALK, ACVRL1 | IDO1 1145/4885AKR1C3 144/4885TSHR 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.