Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.77 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.77 |
| ▸ | ITGAV | P06756 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443090 | 0.87 | ITGB3 (1.00) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7274636 | 0.86 | ITGB3 (0.98) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8720908 | 0.85 | ITGB3 (0.98) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8720937 | 0.84 | ITGB3 (0.92) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8713012 | 0.84 | ITGB3 (0.67) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8713009 | 0.84 | ITGB3 (0.67) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL3268531 | 0.83 | ITGB3 (0.65) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7400070 | 0.83 | ITGB3 (0.65) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL6032775 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8720431 | 0.82 | ITGB3 (0.92) | ITGB3ITGA2BITGAVCHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1205687-A | Tyrosin-derivate as alpha-V-integrin inhibitors | MERCK PATENT GES MIT BESCHR KT (DE) | 1999-01-20 | — | — | CN | disclosed |
| EP-0879227-A1 | TYROSIN-DERIVATE AS ALPHA-V-INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997023451-A1 | TYROSIN-DERIVATE AS ALPHA-V-INTEGRIN INHIBITORS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-07-03 | — | — | WO | disclosed |