Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.83 |
| ▸ | RAD52 | P43351 | 3/20 | 0.83 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.83 |
| ▸ | MMP2 | P08253 | 1/20 | 0.83 |
| ▸ | MC4R | P32245 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | TP53 | P04637 | 1/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.82 |
| ▸ | HTT | P42858 | 4/20 | 0.79 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.79 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10943210 | 1.00 | HSP90AA1 (0.83) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL7760909 | 1.00 | HSP90AA1 (0.83) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL7764496 | 1.00 | HSP90AA1 (0.83) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL8719712 | 1.00 | HSP90AA1 (0.83) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL9730066 | 0.94 | HSP90AA1 (0.75) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL4981893 | 0.93 | HSP90AA1 (0.73) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL14742740 | 0.93 | HSP90AA1 (0.73) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| SCHEMBL25544437 | 0.92 | DNM1 (0.73) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL31268632 | 0.91 | HSP90AA1 (0.71) | HSP90AA1RAD52PSMD14MMP2MC4R | |
| Hydrochloric Acid SCHEMBL31388368 | 0.91 | HSP90AA1 (0.71) | HSP90AA1RAD52PSMD14MMP2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825175-A1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |