Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.61 |
| ▸ | CRHBP | P24387 | 2/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655294 | 0.84 | NPY1R (0.65) | HDAC3HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL29456754 | 0.84 | EPHX1 (0.61) | HDAC3HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL9394260 | 0.83 | CRHBP (0.56) | HDAC3HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL10869967 | 0.83 | ALDH1A1 (0.60) | HDAC3HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL2357262 | 0.83 | HDAC1 (0.60) | HDAC3HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL2357257 | 0.83 | HDAC1 (0.60) | HDAC3HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL7074213 | 0.82 | POLB (0.61) | HDAC3HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL2839194 | 0.82 | EPHX1 (0.62) | HDAC3HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL20869064 | 0.81 | CRHBP (0.54) | HDAC3HDAC1HDAC4HDAC8HDAC6 | |
| SCHEMBL2352398 | 0.81 | HDAC3 (0.51) | HDAC3HDAC1HDAC4HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745154-B1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM | LIGNOZYM GMBH (DE) | 1998-09-16 | — | — | EP | claimed |