Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 4/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL700981 | 1.00 | BLM (0.50) | BLMPMP22APPNFKB1LMNA | |
| Sulfuric Acid SCHEMBL21552193 | 0.97 | BLM (0.48) | BLMPMP22APPNFKB1LMNA | |
| Sulfuric Acid SCHEMBL11142445 | 0.97 | BLM (0.48) | BLMPMP22APPNFKB1LMNA | |
| Sulfuric Acid SCHEMBL11139996 | 0.97 | BLM (0.48) | BLMPMP22APPNFKB1LMNA | |
| Sulfuric Acid SCHEMBL8506691 | 0.91 | APP (0.52) | BLMPMP22APPNFKB1LMNA | |
| Putrescine SCHEMBL1064438 | 0.87 | APP (0.61) | BLMPMP22APPNFKB1LMNA | |
| Putrescine SCHEMBL27732712 | 0.85 | APP (0.68) | BLMPMP22APPNFKB1LMNA | |
| Sulfuric Acid SCHEMBL1065044 | 0.84 | APP (0.58) | BLMPMP22APPNFKB1LMNA | |
| Sulfuric Acid SCHEMBL31657006 | 0.84 | APP (0.58) | BLMPMP22APPNFKB1LMNA | |
| Sulfuric Acid SCHEMBL1063479 | 0.84 | APP (0.58) | BLMPMP22APPNFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801022-A | Method of producing a product with crosslinked crystals of thermolysin | VERTEX PHARMACEUTICALS, INCORPORATED (US) | 1998-09-01 | — | — | US | disclosed |
| WO-1985000381-A1 | PROTEINS, PHARMACEUTICAL COMPOSITIONS, GENES, VECTORS, HOST ORGANISMS AND PROCESSES FOR THEIR PRODUCTION | CELLTECH LIMITED (GB) | 1985-01-31 | — | — | WO | disclosed |
| EP-0131418-A1 | Proteins, pharmaceutical compositons, genes, vectors, host organisms and processes for their production | CELLTECH LIMITED (GB) | 1985-01-16 | — | — | EP | disclosed |
| US-4271269-A | Regeneration of an enzyme immobilizate | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | disclosed |