Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Putrescine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 4/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 4/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA3 | P07451 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA6 | P23280 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1063479 | 0.96 | APP (0.58) | APPBLMPMP22NFKB1CA5A | |
| Sulfuric Acid SCHEMBL1065044 | 0.96 | APP (0.58) | APPBLMPMP22NFKB1CA5A | |
| Diaminooctane SCHEMBL31657028 | 0.96 | APP (0.58) | APPBLMPMP22NFKB1CA5A | |
| Sulfuric Acid SCHEMBL31657006 | 0.96 | APP (0.58) | APPBLMPMP22NFKB1CA5A | |
| Sulfuric Acid SCHEMBL9502809 | 0.93 | APP (0.55) | APPBLMPMP22NFKB1CA5A | |
| Sulfuric Acid SCHEMBL4382219 | 0.92 | APP (0.61) | APPBLMPMP22NFKB1CA5A | |
| Sulfuric Acid SCHEMBL11338464 | 0.92 | APP (0.61) | APPBLMPMP22NFKB1CA5A | |
| Sulfuric Acid SCHEMBL27569908 | 0.89 | APP (0.58) | APPBLMPMP22NFKB1CA5A | |
| Sulfuric Acid SCHEMBL8722128 | 0.87 | BLM (0.50) | APPBLMPMP22NFKB1CA5A | |
| Sulfuric Acid SCHEMBL700981 | 0.87 | BLM (0.50) | APPBLMPMP22NFKB1CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116904357-A | Strain capable of tolerating high-concentration 1,4-butanediamine as well as culture method and application thereof | 天津科技大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116904357-A | Strain capable of tolerating high-concentration 1,4-butanediamine as well as culture method and application thereof | 天津科技大学 | 2023-10-20 | — | — | CN | disclosed |
| EP-3682864-A1 | USE OF A DIAMINE TO IMPROVE THE MECHANICAL STRENGTH OF HAIR, AND HAIR CARE AGENT CONTAINING SAME | Obshchestvo S Ogranichennoj Otvetstvennostyu "Yunikosmetik" (RU) | 2020-07-22 | — | — | EP | disclosed |
| CN-107614479-A | Method for purifying 1,4 diaminobutanes | CJ第制糖株式会社 | 2018-01-19 | — | — | CN | disclosed |
| EP-2263996-B1 | PROCESS FOR PRODUCING DIAMINE AND POLYAMIDE | TORAY INDUSTRIES (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-8334411-B2 | Process for producing diamine and polyamide | TORAY INDUSTRIES, INC. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20110004018-A1 | PROCESS FOR PRODUCING DIAMINE AND POLYAMIDE | TORAY INDUSTRIES, INC. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2263996-A1 | PROCESS FOR PRODUCING DIAMINE AND POLYAMIDE | Toray Industries, Inc. (JP) | 2010-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004018-A1 | PROCESS FOR PRODUCING DIAMINE AND POLYAMIDE | NAAA, PUF60, DNPEP | SLC6A2 191/4885SLC6A3 272/4885APP 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.