Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.34 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL1171068 | 0.90 | TSHR (0.48) | TSHRMAPK1MEN1KMT2ARNPEP | |
| Di(Hydroxyethyl)Ether SCHEMBL29239546 | 0.90 | TSHR (0.48) | TSHRMAPK1MEN1KMT2ARNPEP | |
| Di(Hydroxyethyl)Ether SCHEMBL29124601 | 0.90 | TSHR (0.48) | TSHRMAPK1MEN1KMT2ARNPEP | |
| Alanine SCHEMBL19668572 | 0.88 | TSHR (0.42) | TSHRMAPK1GABRR1MEN1KMT2A | |
| Triethylene Glycol SCHEMBL14964597 | 0.88 | MEN1 (0.50) | TSHRMAPK1MEN1KMT2ARNPEP | |
| Acetic Acid SCHEMBL4393167 | 0.81 | TSHR (0.48) | TSHRMAPK1GABRR1MEN1KMT2A | |
| Monoethanolamine SCHEMBL3728867 | 0.81 | GABRR1 (0.48) | TSHRGABRR1MEN1KMT2ARNPEP | |
| SCHEMBL8722994 | 0.78 | CPB2 (0.33) | TSHRMAPK1GABRR1MEN1KMT2A | |
| Glycine SCHEMBL25308690 | 0.77 | TSHR (0.48) | TSHRMAPK1GABRR1MEN1KMT2A | |
| Tetraethylene Glycol SCHEMBL1052486 | 0.77 | MEN1 (0.52) | TSHRMAPK1GABRR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834224-A | DETERMINATION OF ANALYTE BY ELECTROCHEMICAL MEASUREMENT | BOEHRINGER MANNHEIN GMBH (DE) | 1998-11-10 | — | — | US | disclosed |
| US-5763191-A | BINDING MATRIX | BOEHRINGER MANNHEIM GMBH (DE) | 1998-06-09 | — | — | US | disclosed |