Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654774 | 0.85 | RECQL (0.41) | MEN1KMT2ARECQLALDH1A1POLB | |
| SCHEMBL6971894 | 0.85 | KMT2A (0.42) | MEN1KMT2ARECQLALDH1A1POLB | |
| SCHEMBL7661454 | 0.83 | MTNR1A (0.55) | RECQLALDH1A1POLBMTNR1AMTNR1B | |
| SCHEMBL7668480 | 0.80 | RECQL (0.40) | MEN1KMT2ARECQLALDH1A1POLB | |
| SCHEMBL7662670 | 0.80 | RECQL (0.47) | MEN1KMT2ARECQLALDH1A1POLB | |
| SCHEMBL8099535 | 0.79 | RECQL (0.41) | MEN1KMT2ARECQLALDH1A1POLB | |
| SCHEMBL7657111 | 0.79 | GLA (0.40) | MEN1KMT2ARECQLALDH1A1POLB | |
| SCHEMBL7659317 | 0.79 | CTSC (0.40) | MEN1KMT2ARECQLALDH1A1POLB | |
| SCHEMBL7660171 | 0.79 | MEN1 (0.51) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL7664251 | 0.78 | RECQL (0.40) | MEN1KMT2ARECQLALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861243-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997011069-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-27 | — | — | WO | disclosed |