Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971894 | 0.81 | KMT2A (0.42) | RECQLMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL8722188 | 0.79 | MEN1 (0.39) | RECQLMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL5238931 | 0.79 | AKR1C3 (0.48) | RECQLMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7663086 | 0.78 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL7663170 | 0.77 | RECQL (0.41) | RECQLMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7661454 | 0.77 | MTNR1A (0.55) | RECQLMTNR1AMTNR1BALDH1A1POLB | |
| SCHEMBL7662670 | 0.76 | RECQL (0.47) | RECQLMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7668480 | 0.76 | RECQL (0.40) | RECQLMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7670340 | 0.76 | ALDH1A1 (0.44) | RECQLMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7654774 | 0.76 | RECQL (0.41) | RECQLMEN1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140341-A | FOR TREATING PAIN | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-10-31 | — | — | US | disclosed |
| EP-0795547-B1 | (Aminoalkyl- and acylaminoalkyl-oxy)benzyloxyquinolines, process for their preparation and use as Bradykinin receptor antagonists | HOECHST AG (DE) | 2000-05-10 | — | — | EP | disclosed |
| EP-0795547-A1 | (Aminoalkyl- and acylaminoalkyl-oxy)benzyloxyquinolines, process for their preparation and use as Bradykinin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |