SCHEMBL8722201

SCHEMBL8722201

O=C(NCc1ccccn1)c1ccccn1

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.69
HPGD P15428 5/20 0.68
ALDH1A1 P00352 4/20 0.68
POLB P06746 2/20 0.68
RAB9A P51151 2/20 0.63
KMT2A Q03164 2/20 0.63
MAPK1 P28482 1/20 0.63
NPC1 O15118 2/20 0.63
LMNA P02545 2/20 0.63
HTT P42858 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C19 P33261 1/20 0.61
GLS O94925 1/20 0.60
KDM4E B2RXH2 1/20 0.60
HSD17B10 Q99714 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16598445 0.86 HTT (0.66) SMN1; SMN2HPGDALDH1A1POLBKMT2A
SCHEMBL4174785 0.86 SMN1; SMN2 (0.59) SMN1; SMN2HPGDALDH1A1POLBRAB9A
SCHEMBL7975613 0.84 TSHR (0.68) SMN1; SMN2HPGDALDH1A1KMT2AMAPK1
SCHEMBL31098478 0.84 HTT (0.63) SMN1; SMN2HPGDALDH1A1KMT2AMAPK1
SCHEMBL20610606 0.84 HPGD (0.60) SMN1; SMN2HPGDALDH1A1POLBRAB9A
SCHEMBL8722345 0.83 KMT2A (0.65) SMN1; SMN2ALDH1A1POLBRAB9AKMT2A
SCHEMBL29733373 0.83 HTT (0.75) SMN1; SMN2HPGDALDH1A1KMT2AMAPK1
SCHEMBL3083971 0.83 HTT (0.75) SMN1; SMN2HPGDALDH1A1KMT2AMAPK1
SCHEMBL166484 0.83 LMNA (0.82) SMN1; SMN2HPGDALDH1A1POLBRAB9A
SCHEMBL1014325 0.82 LMNA (0.63) SMN1; SMN2HPGDALDH1A1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102268027-B Amide Au (III) complex with antitumor activity UNIV HEBEI 2013-11-13 CN claimed
US-4678794-A N-pyridyl-substituted pyridine-2-carboxamide-1-oxides JOHN WYETH & BROTHER LIMITED (GB) 1987-07-07 US claimed
CN-115057894-B Environment-friendly drier, and preparation method and application thereof 上海佰奥聚新材料科技有限公司 2024-04-05 CN disclosed
US-10184052-B2 Near infrared radiation-absorbing composition, near infrared radiation cut-off filter and production method therefor, and camera module and production method therefor FUJIFILM CORPORATION (JP) 2019-01-22 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
WO-2015048503-A2 N-ARYLMETHYL SULFONAMIDE NEGATIVE MODULATORS OF NR2A MNEMOSYNE PHARMACEUTICALS, INC. (US) 2015-04-02 WO disclosed
CN-102268027-B Amide Au (III) complex with antitumor activity UNIV HEBEI 2013-11-13 CN disclosed
US-5789138-A Optical recording medium and method of producing the same RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 SMN1; SMN2 2133/4885HPGD 4594/4885ALDH1A1 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.