Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479832 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HPGDL3MBTL1NPC1 | |
| SCHEMBL8722612 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HPGDL3MBTL1NPC1 | |
| SCHEMBL11778291 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDL3MBTL1NPC1 | |
| SCHEMBL8719156 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1LMNAAKR1C3AKR1C2 | |
| SCHEMBL8719159 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1LMNAAKR1C3AKR1C2 | |
| SCHEMBL11780959 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1HPGDL3MBTL1NPC1 | |
| SCHEMBL8859936 | 0.84 | FLT3 (0.41) | KDM4EALDH1A1HPGDL3MBTL1NPC1 | |
| SCHEMBL11839741 | 0.82 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDL3MBTL1NPC1 | |
| SCHEMBL10859955 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDL3MBTL1NPC1 | |
| SCHEMBL28917247 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1HPGDL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750764-A | Synthesis and resolution of propionic acid derivatives | AECI LIMITED (ZA) | 1998-05-12 | — | — | US | disclosed |
| WO-1997019048-A1 | SYNTHESIS OF PROPIONIC ACID DERIVATIVES | AECI LIMITED (ZA) | 1997-05-29 | — | — | WO | disclosed |